Which statement about chylomicrons is FALSE?

• A. The major lipid transported by this lipoprotein is cholesterol.
• B. This lipoprotein is produced in the intestinal mucosa.
• C. The primary function is to carry dietary (exogenous) lipids to the liver.
• D. It remains at the origin (point of application) during lipoprotein electrophoresis.

Answer: (A)

Chylomicrons are the lipoproteins formed in intestinal mucosa that shuttle dietary triglycerides from the gut to peripheral tissues, with remnants eventually taken up by the liver. The lipid they carry in greatest amount is triglycerides, not cholesterol, so stating that cholesterol is the major lipid transported is incorrect. They are indeed produced in the intestinal mucosa, and their main function is to deliver exogenous lipids to tissues (and to the liver as remnants after lipolysis). In lipoprotein electrophoresis, chylomicrons largely stay near the origin due to their large size and high triglyceride content.